ABSTRACT
@#Neuroendocrine tumours (NETs) are a category of neoplasm that is characterised by its phenotypic and heterogeneity. The occurrence of this type of neoplasm in the nasal cavity and paranasal sinuses is extremely rare accounting for only 0.2-0.8% of all cancers. NET tends to expresses somatostatin receptors (SSTR) and owning to this unique characteristic, molecular imaging has been able to detect these tumours using radiolabelled somatostatin analogue agent. Gallium-68 (Ga-68) DOTATATE PET/CT is an example of SSTR imaging and has been shown to be of importance in the assessment and staging of NET. We present a case of a rare sphenoid sinus NET in a 45-year-old gentleman whom initially presented with persistent left eye pain which led to visual loss. We described the utilization of Ga-68 DOTATATE PET/CT in the diagnosis and staging of this patient which in turn dictated treatment approach.
ABSTRACT
@#Mycoplasma pneumoniae is frequently known as an “atypical bacterium” that can cause wide-ranging extrapulmonary manifestations. Here, we outline a case of a child, aged 9-year-old, who presented with profound proximal muscle weaknesses and a vague rash, associated with markedly elevated serum creatinine kinase (CK). Muscle biopsy suggested Juvenile Dermatomyositis (JDM) following an upper respiratory illness of M. pneumoniae origin. The child responded exceptionally well to a combined therapy of immunoglobulin, intravenous glucocorticoid and methotrexate.